ATM4 — Lactuca sativa

Summary

LsATM4, also known as ATM4, is a garden lettuce gene on chromosome 3 that encodes a protein with a Myb domain and SANT/Myb domain, and has DNA binding, transcription factor activity, and protein dimerization activity. It is associated with the regulation of anthocyanin, flavonoid, proanthocyanidin, glucosinolate, and raffinose metabolic processes, as well as cellular detoxification of cadmium ions, response to sulfur starvation, trichome morphogenesis and spacing, plant epidermal cell fate specification, defense response to insects, cutin biosynthesis, and drought recovery. The gene product localizes to the nucleus, cytosol, root hair, and preprophase band. Associations with traits such as leaf trichome density, seed protein content, phosphorus response, shoot elongation under submergence, and branch angle have been noted. Studies of related genes in other species link the family to cuticle development, suberin biosynthesis, glucosinolate accumulation, and drought response.