ATM4 — Lactuca sativa

Summary

LsATM4, also known as ATM4, is a garden lettuce gene on chromosome 3 that encodes a MYB-domain transcription factor with DNA-binding, chromatin-binding, protein-dimerization, and transcription-factor-binding activities. In lettuce, LsATM4 is associated with the regulation of raffinose metabolism, glucosinolate biosynthesis, proanthocyanidin and flavonoid anabolism, anthocyanin production, trichome morphogenesis and spacing, cutin anabolism, defense responses to insects, cellular detoxification of cadmium ions, response to sulfur starvation, and drought recovery. The gene product localizes to the nucleus, cytosol, root hair, and preprophase band. Studies of related genes in other species link the family to traits including glucosinolate content, cuticle and suberin deposition, trichome differentiation, root epidermal patterning, cadmium accumulation, and drought and salt stress tolerance.