ADH — Hordeum vulgare subsp. vulgare

Summary

HORVU.MOREX.R3.4HG0406770 (HvADH) on barley chromosome 4H encodes an alcohol dehydrogenase with S-(hydroxymethyl)glutathione dehydrogenase, S-nitrosoglutathione reductase and aldo-keto reductase activities, binding zinc and calcium. The gene is associated with ethanol fermentation, cellular respiration, and responses to hypoxia, flooding, hydrogen peroxide, and sucrose. It has been linked to grain yield, grain dry weight, seed size, germination rate, protein content, photosynthetic rate, leaf senescence, and tolerance to drought, low temperature, salinity, and disease. Associations also include submergence, waterlogging, hypoxia, and cold stress tolerance, as well as aldehyde detoxification, herbicide sensitivity, and root growth. The protein localises to the cytosol, plastid, mitochondria, nucleus, and plasmalemma. Studies of related genes in other species link the family to hypoxia, dehydration, freezing, and salt stress responses, and to submergence tolerance.