MLO — Hordeum vulgare subsp. vulgare

Summary

HORVU.MOREX.R3.4HG0410620 (symbol MLO) on barley chromosome 4H encodes a calmodulin-binding protein with additional protein-binding activity. The gene is associated with host invasion, invasive growth, cell polarization, endosomal transport, pollen tube reception and guidance, intracellular transport, protein localization to the plasma membrane, metabolic burst, protein polyubiquitination, virus-induced PTGS, protein breakdown, vesicle transport, downregulation of defense response, immune response, and response to fungi. It is linked to leaf necrosis, leaf chlorosis, grain yield, root gravity response, Botrytis cinerea resistance, leaf senescence, callose deposition, systemic acquired resistance, root thigmomorphogenesis, and pollen-related processes. The protein localizes to root hairs, endomembrane system, Golgi complex, plasmodesmata, extracellular space, mitochondria, membrane, plasmalemma, and cytoplasm. Studies of related genes in other species connect the family to powdery mildew resistance, disease resistance and susceptibility, ozone tolerance, and fertilization.