scd1 — Fusarium oxysporum f. sp. lycopersici 4287

Summary

FOXG_18858 (symbol scd1) on chromosome 4 of Fusarium oxysporum f. sp. lycopersici 4287 encodes a protein containing a Cdc24/Scd1_N domain and a PH-like domain superfamily, with annotated GDS and lipid-binding molecular functions. The gene is associated with regulation of mitotic spindle organization, regulation of conjugation with cellular fusion, upregulation of mating projection assembly, septin ring organization, regulation of division septum assembly, regulation of endocytosis, establishment or maintenance of bipolar cell polarity, division septum assembly, cell polarization, translation elongation, intracellular signal transduction, and mating. Its product localizes to the cleavage furrow, cortical dynamic polarity patches, cell cortex of growing cell tip, sites of polarized growth, mating projection tip, division septum, plasma membrane at cell tip, cell cortex of cell tip, mitotic spindle, and cell tip. Studies of related genes in other species link the family to the Cdc42 GTPase complex.