ARF1 — Fusarium oxysporum f. sp. lycopersici 4287

Summary

FOXG_20096 (ARF1) on chromosome 11 of Fusarium oxysporum f. sp. lycopersici 4287 encodes a small GTPase of the ARF/SAR family, with GTP binding, GTPase activity and G protein activity. The gene is associated with vesicle organization, ER-to-Golgi transport, secretion, intracellular protein transport, mitochondrial fission, and membrane and nuclear envelope organization. It is linked to positive regulation of protein exit from the ER and upregulation of ER-to-Golgi transport, as well as cellular response to active oxygen species. The encoded protein localizes to the ER membrane, Golgi complex, COPII vesicle coat, ER exit site, mitochondria-associated membrane, mitochondria, plasmalemma and cytoplasm. Studies of related genes in other species link the family to GTPase activity (EC 3.6.5.2).