ADH1 — Fusarium oxysporum f. sp. lycopersici 4287

Summary

FoADH1 (FOXG_17476) on chromosome supercont2.50 of Fusarium oxysporum f. sp. lycopersici 4287 encodes an aldo-keto reductase with NAD activity and zinc binding, belonging to the ADH-like family. This gene is associated with the breakdown of acetaldehyde, ethanol, and threonine, as well as cellular response to farnesol. Its product localises to the cytoplasm, mitochondrial lumen, extracellular region, and fungal biofilm matrix. FoADH1 is linked to the related genes patD, alcC, ADH2, and ADH6. Studies of related genes in other species, including Fusarium species and Verticillium, connect the family to alcohol metabolism, though these associations are not yet established for FoADH1 itself.