AP2A1 — Daucus carota subsp. sativus

Summary

DCAR_018747 (DcAP2A1) on carrot chromosome 5 encodes a large subunit of the AP-2 clathrin adaptor complex, with clathrin adaptor, phospholipid binding, and structural molecule activities. It is associated with clathrin-mediated endocytosis, auxin polar transport and export across the plasma membrane, positive gravitropism, and responses to hypoxia, glucose, ethylene, and auxin. The protein localises to the clathrin adaptor complex, basal plasma membrane, trans-Golgi network, and cell plate. DcAP2A1 is linked to root branching, lateral root number and length, root hair length, root mass density, root thickness, phototropism, biomass yield, stamen length, brassinosteroid sensitivity, ethylene sensitivity, disease tolerance, and self-incompatibility. Studies of related genes in other species connect the family to polar subcellular localisation, root growth direction, cell elongation, biomass production, and root circumnutation.