SDH — Daucus carota subsp. sativus

Summary

DCAR_018856 (SDH) on carrot chromosome 5 encodes a short-chain dehydrogenase/reductase (SDR) family protein with an NAD(P)-binding domain. The enzyme exhibits multiple oxidoreductase activities, including momilactone-A synthase, zerumbone synthase, (+)-borneol dehydrogenase, secoisolariciresinol dehydrogenase, and xanthoxin dehydrogenase (NAD+) activity, all acting on CH-OH groups with NAD or NADP as acceptor. The gene is associated with terpenoid, monoterpenoid, lignan, phenylpropanoid, and abscisic acid biosynthesis, as well as small molecule biosynthesis. It has been linked to responses to UV, jasmonic acid, and wounding, and to spore germination and protein homotetramerization. The product localizes to mitochondria and the cytosol. Studies of related genes in other species connect the SDR family to additional alcohol dehydrogenase activities (EC 1.1.1.1, 1.1.1.198, 1.1.1.295, 1.1.1.326, 1.1.1.331).