HSP70 — Daucus carota subsp. sativus

Summary

DCAR_009834, designated DcHSP70 (also known as HSP70-17) on carrot chromosome 3, encodes a member of the heat shock 70 kDa protein family, characterised by an ATPase nucleotide-binding domain and a peptide-binding domain, and functions as an ATP hydrolase, a protein-folding chaperone and a heat shock protein binding protein. The gene is associated with the unfolded protein response, the ERAD pathway, homologous recombination, protein refolding and folding in the endoplasmic reticulum, and responses to heat, stress, virus and wounding. It is linked to thermotolerance, heat and abiotic stress responses, radiation response and photosynthetic rate. The protein localises to the ER lumen and chaperone complex, chloroplast membrane, tonoplast, Golgi, secretory vesicles and the mediator complex. Studies of related genes in other species connect the family to heat, drought and salt stress tolerance.