E2F1 — Daucus carota subsp. sativus

Summary

DCAR_010316 (DcE2F1) on carrot chromosome 3 encodes an uncharacterized protein with E2F and winged-helix DNA-binding domains, annotated with DNA-binding transcription factor activity, RNA polymerase II-specific cis-regulatory region binding, DNA damage sensor activity, and protein heterodimerization activity. The gene is associated with cell cycle regulation, including G1/S transition, and modulation of cell proliferation, as well as trichome morphogenesis, programmed cell death, and responses to auxin, jasmonic acid, ethylene, and salicylate. It localises to the nucleus, cytoplasm, and RNA polymerase II transcription regulator complex, and is linked to nitrate uptake, cell cycle duration, root growth, virus resistance, and DNA damage response. Related genes in other species connect the family to endoreduplication, leaf development, cell division, and geminivirus susceptibility, while sequence similarity links extend to drought tolerance, plant height, and water use efficiency.