CAF — Daucus carota subsp. sativus

Summary

DCAR_010108 (DcCAF) on carrot chromosome 3 encodes a protein with domains characteristic of a Dicer-like RNase III enzyme, including a DEAD/DEAH-box helicase domain, RNase III domain, and dsRNA-binding motifs. The gene product is annotated with ribonuclease III activity, helicase activity, dsRNA binding, and miRNA binding, and is associated with small RNA processing pathways including LsiRNA, pre-miRNA, and ta-siRNA processing, as well as gene silencing by miRNA-mediated mRNA cleavage. In carrot, DcCAF has been linked to soluble sugar content. The gene is further associated with numerous developmental and stress-related traits, including leaf and floral morphology, seed development and dormancy, root meristem development, viral disease response, herbivore resistance, and resistance to fungal pathogens such as Fusarium brachygibbosum and Sclerotinia sclerotiorum. It localizes to the nucleus, nucleolus, cytosol, and other subcellular compartments.