F3H — Daucus carota subsp. sativus

Summary

DCAR_009483 (F3H-1, DcF3H) on carrot chromosome 3 encodes a 2-oxoglutarate/Fe(II)-dependent dioxygenase with flavanone 3-dioxygenase, flavonol synthase, and flavone synthase activities, and also annotated chalcone isomerase activity. The enzyme binds vitamin C and metals. F3H-1 is associated with anthocyanin, flavonoid, and coumarin biosynthesis, responses to UV-B, UV, auxin, and fungal molecules, and root development. It localises to the cytosol, nucleus, endoplasmic reticulum, and tonoplast. The gene is linked to root colour, anthocyanin and flavonoid content, UV-B sensitivity, oxidative stress response, and stamen morphology. Associations also include powdery mildew resistance, pollen traits (germination, tube elongation, viability, thermotolerance), lateral root and root hair formation, cold acclimation, and proanthocyanidin accumulation. Related genes in other species connect the family to seed coat pigmentation, UV-B tolerance, and flavonol biosynthesis.