F3H — Daucus carota subsp. sativus

Summary

DCAR_009488 (DcF3H) on carrot chromosome 3 encodes a 2-oxoglutarate/Fe(II)-dependent dioxygenase with flavanone 3-dioxygenase, flavone synthase, flavonol synthase and chalcone isomerase activities, and binds vitamin C and metals. The gene is associated with anthocyanin, flavonoid and coumarin biosynthesis, responses to UV, UV-B, fungal molecules and auxin, and root development. It localises to the tonoplast, ER, cytosol, cytoplasm and nucleus. Associations include root colour, anthocyanin and flavonoid content, stamen morphology, root phototropism, UV-B sensitivity, oxidative stress response, powdery mildew resistance, pollen traits (germination, tube elongation, viability, thermotolerance), lateral root and root hair formation, cold acclimation, proanthocyanidin accumulation, and pathogen response. Studies of related genes in other species link the family to seed coat pigmentation, UV-B tolerance, flavonol and glucosinolate biosynthesis, and stress tolerance.