F3H — Daucus carota subsp. sativus

Summary

DCAR_009487 (DcF3H) on carrot chromosome 3 encodes a protein with flavanone 3-dioxygenase, flavone synthase, flavonol synthase and chalcone isomerase activities, and binds vitamin C and metals. The gene is associated with anthocyanin, flavonoid and coumarin biosynthesis, responses to UV-B, UV, auxin and fungal molecules, and root development. It localises to the tonoplast, endoplasmic reticulum, cytosol and nucleus. DcF3H is linked to root colour, anthocyanin and flavonoid content, UV-B sensitivity, oxidative stress response, stamen morphology and root phototropism. Phenotypic associations include anthocyanin and proanthocyanidin accumulation, pollen traits (germination, tube elongation, viability, thermotolerance), powdery mildew resistance, lateral root and root hair formation, cold acclimation, circadian clock regulation, photosynthetic activity and genome stability. Studies of related genes in other species connect the family to seed coat pigmentation, UV-B tolerance and flavonol biosynthesis.