MLO — Cucumis sativus

Summary

CSA_6G078520, designated MLO (also known as MLO15, CsMLO, CsMLO1, CsMLO15), encodes a calmodulin-binding protein in cucumber (Cucumis sativus) chromosome 6. The gene is associated with cell wall thickening, immune and defense responses, cell death, calcium and ABA signaling, signal transduction, and protein synthesis. Its product localizes to the membrane and plasmalemma and is linked to root hair development. The gene has been connected to pollen tube guidance and disease tolerance, including wheat powdery mildew disease response. Studies of related MLO family members in other species link the family to powdery mildew susceptibility and resistance, bacterial wilt resistance, and resistance to Corynespora cassiicola, as well as to protein interactions.