FC1 — Cucumis sativus

Summary

CsFC1 (CSA_6G135440, also known as HEMH, FC1, and FC2) in cucumber (Cucumis sativus) encodes a ferrochelatase with protoheme ferrolyase activity (EC 4.98.1.1). The protein contains ferrochelatase N, AS, and C domains and localizes to plastids, thylakoid membranes, and mitochondria. This gene is associated with porphyrin-containing compound, tetrapyrrole, heme, chlorophyll, and carotenoid biosynthesis, as well as photoprotection, lipid oxidation, regulation of gene expression, and response to oxidative stress. It has been linked to plant height, proline content, salt stress tolerance, seedling development, chlorophyll accumulation, photosynthesis-associated nuclear gene expression, embryogenesis, and defective de-etiolation with ROS accumulation and chloroplast degradation. Related genes in other species are associated with salt and cadmium tolerance, chloroplast function, and tissue development.

Annotations

Chromosome
6
Related genes
FC1, FC2
GO terms
Photoprotection, tetrapyrrole anabolism, Porphyrin-containing Compound Biosynthetic Process, protoheme ferrolyase activity, carotenoid anabolism, Lipid Oxidation, heme anabolism, Plastid
Publications
18433503, 35166359, 36266500, 16615871, 15028209, PMID:16618929, PMID:32779277, 17408486
Traits
Defective De-etiolation, ROS Accumulation, Chloroplast Degradation, Abnormal Chloroplasts, ROS Production, No Chloroplast Degradation, haem biosynthesis, stress response, tissue development, oxidative stress response, photosynthesis-associated nuclear gene expression, seedling development