MLO — Cucumis sativus

Summary

CSA_6G292430 (MLO) on cucumber chromosome 6 encodes a calmodulin-binding, membrane-associated protein with molecular functions including calmodulin binding and protein binding. The gene is associated with defense responses against fungi and bacteria, immune response, cell wall thickening, and downregulation of defense response, and is localized to the plasmalemma, Golgi complex, plasmodesmata, and extracellular regions. It has been associated with Botrytis cinerea resistance, leaf senescence, callose deposition, and systemic acquired resistance. Studies of related MLO family members in other species connect the family to powdery mildew resistance and susceptibility, bacterial wilt susceptibility, heat tolerance, and ozone tolerance, as well as traits including water use efficiency, seed maturation, stomatal resistance, and disease tolerance.