ZAT — Cucumis sativus

Summary

CsZAT (CSA_6G080940) in cucumber encodes a metal tolerance protein 1-like member of the CDF/SLC30A cation efflux family, with metal ion transmembrane transporter activity and specific zinc ion transmembrane transporter activity. The protein localises to the vacuolar membrane, tonoplast, ER membrane and Golgi complex. CsZAT is associated with detoxification of zinc and cobalt ions, cellular zinc ion homeostasis, zinc transport, and defence and antiviral responses. It has been linked to zinc sensitivity, zinc tolerance, cadmium detoxification, zinc partitioning and storage, and root growth. Studies of related genes in other species connect the family to zinc accumulation, cadmium tolerance, heavy metal tolerance, and cobalt tolerance, as well as leaf chlorosis, root morphology and seed dormancy traits.