NHX1 — Cucumis sativus

Summary

CsNHX1 (CSA_6G067980) on cucumber chromosome 6 encodes a sodium/hydrogen exchanger belonging to the CPA1 family, with lithium:proton and potassium:proton antiporter activities. It is associated with vacuolar membrane transport, sodium import, lithium export, cell pH regulation, and response to superoxide. The gene has been linked to numerous agronomically important traits including yield, plant height, root development, chlorophyll content, photosynthetic rate, stomatal resistance, and stress responses. Additional associations include sodium exclusion, auxin content, abscisic acid sensitivity, and plant growth and development traits. The protein localizes to the tonoplast, vacuole, endosome, and plastid, and is connected to brassinosteroid and nitric oxide anabolism. Related genes in other species link the gene family to vacuolar pH homeostasis, ion transport, and stress tolerance.