TCP — Capsicum annuum

Summary

T459_06507, the TCP gene on pepper chromosome 2, encodes a chaperonin subunit zeta (TCP-1 family protein) with ATP-dependent protein folding chaperone activity, ATP hydrolase activity, and ATP binding. The gene is associated with protein folding and refolding, fruit development and ripening, leaf and flower development, and carbohydrate, mannose, nucleotide, and sucrose metabolism. It has been linked to protein-peroxisome targeting, response to zinc, and peroxisome function including PTS2 protein import. The encoded protein localizes to the cytosol, cytoplasm, nucleus, plastid, mitochondria, mitochondrial lumen, and the TriC and Cul4-RING E3 ubiquitin ligase complexes. Associations with selenium and sulfur content have been noted. Studies of related genes in other species link the family to cadmium tolerance, nitric oxide production, glyoxysomal function, and PTS1 protein import into peroxisomes, as well as traits including fruit weight, fruit color, seed weight, leaf size, and auxin and cytokinin content.