ICDH — Capsicum annuum

Summary

CaICDH (T459_06843) on pepper chromosome 2 encodes an NADP-dependent isocitrate dehydrogenase (EC 1.1.1.42) with NAD and NADP isocitric dehydrogenase activity, binding NAD, magnesium, copper, ATP, and proteins, and homodimerizing. It is associated with the TCA cycle, glyoxylate cycle, cellular respiration, NAD(P) metabolism, isocitrate metabolism, detoxification, fruit ripening, microsporogenesis, cell growth and death, brassinosteroid-mediated signalling, and defence against bacteria. The protein localizes to chloroplast thylakoid and stroma, plastid, mitochondria, cytosol, apoplast, plasmodesma, and plasmalemma. CaICDH is linked to pungency, cytoplasmic male sterility, respiration and photosynthetic rates, root morphology, nitrogen metabolism, redox homeostasis, histone methylation, and hydraulic conductivity. Studies of related genes in other species connect the family to seed weight, starch, sugar, protein, and chlorophyll content, drought and salt tolerance, disease tolerance, and oxidative stress response.