STH — Capsicum annuum

Summary

CaSTH (T459_07754) on pepper chromosome 3 encodes a pathogenesis-related protein STH-21, a member of the Bet_v_I/MLP and START-like domain superfamilies. The product exhibits nuclease, hydrolase, abscisic acid binding, protein phosphatase inhibitor, and signaling receptor activities. CaSTH is associated with defense responses, systemic acquired resistance, virus-induced post-transcriptional gene silencing, hypersensitivity, cell death, and fruit ripening. It is linked to pathogen response and disease resistance, as well as basophil activation, inflammatory response, secretion, flavonoid anabolism, and ABA signaling. The protein localizes to the cytoplasm and nucleus. Studies of related genes in other species connect the family to pathogen resistance and disease tolerance.