ACO1 — Capsicum annuum

Summary

CaACO1 (T459_07765) on pepper chromosome 3 encodes a 3-isopropylmalate dehydratase large subunit with aconitase activity and intramolecular hydroxytransferase activity, and it binds 4Fe-4S clusters, iron, copper, ATP, and mRNA 5'-UTRs. The gene is associated with the TCA cycle, glyoxylate cycle, leucine biosynthesis, oxoacid and citrate metabolism, and the S-adenosylmethionine cycle. It is linked to leaf senescence, trichome morphogenesis, immune response, regulation of reactive oxygen species, salicylic acid-mediated signaling, and response to iron starvation. Associations with ethylene sensitivity, root morphology, lateral root development, gravitropic response, waterlogging stress tolerance, salt tolerance, and plant growth have been reported. Studies of related genes in other species link the family to ethylene biosynthesis, cytosolic aconitase activity, seed germination, stress response, and fruit shelf-life, while melon ACO1 studies connect the family to fruit softening and shelf-life.