HSP70 — Brachypodium distachyon

Summary

BRADI_1G66470V3 (BdHSP70) on chromosome 1 encodes an ATP-dependent protein folding chaperone belonging to the Hsp70 family, with ATP hydrolase activity and heat shock protein binding capacity. In Brachypodium distachyon, this gene is associated with protein folding in the ER, the ERAD pathway, the unfolded protein response, heat acclimation, and response to heat and stress. It has also been connected to auxin transport and signaling, amino acid membrane transport, and response to virus. The encoded protein localises to the ER lumen and chaperone complex, cytoplasm, nucleus, chloroplast membrane, tonoplast, and membrane. Associations with photosynthetic rate have been noted. Studies of related genes in other species link the Hsp70 family to grain yield, spikelet number, plant height, chlorophyll content, water use efficiency, and tolerance to heat, drought, and rust diseases.