HSP70 — Brachypodium distachyon

Summary

BRADI_1G66520V3 (HSP70) on chromosome 1 of Brachypodium distachyon encodes an EF-hand domain-containing protein belonging to the Hsp70 family, with ATP-dependent protein folding chaperone activity, heat shock protein binding, and ATP hydrolase activity. The gene is associated with protein refolding, the ERAD pathway, the unfolded protein response, heat acclimation, and response to heat and stress. It has also been linked to auxin transport and signaling, basipetal and polar auxin transport, amino acid membrane transport, and response to virus. Localisation evidence connects the product to the ER chaperone complex, ER lumen, chloroplast membrane, cytoplasm, and nucleus. Additionally, the gene is associated with spikelet number. Studies of related genes in other species link the family to similar chaperone functions in protein folding and stress responses.