stcO — Aspergillus nidulans FGSC A4

Summary

ANIA_07811 (stcO) on chromosome 4 of Aspergillus nidulans FGSC A4 encodes a protein with a Polyketide_Oxido-like domain and NAD(P)-binding domains, annotated as an oxidoreductase acting on CH-NH group donors with NAD or NADP as acceptor, and as a monooxygenase with redox activity (EC 1.-.-.-). This gene is associated with the biosynthesis of several secondary metabolites, including xanthones, monodictyphenone, sterigmatocystin, and aflatoxin, as well as general secondary metabolite biosynthesis. It is also linked to sexual reproduction. The encoded protein is associated with membrane localization. Studies of related genes in other species connect the family to oxidoreductase functions.