stcW — Aspergillus nidulans FGSC A4

Summary

ANIA_07804 (stcW) on chromosome 4 of Aspergillus nidulans encodes a flavin-containing monooxygenase with N,N-dimethylaniline monooxygenase activity, also annotated for methyltransferase activity and NADP and FAD binding. The product belongs to the FAD-binding monooxygenase superfamily. stcW is associated with the biosynthesis of several secondary metabolites, including fumagillin, aflatoxin, and sterigmatocystin, as well as with fermentation and methylation processes. The protein is linked to membrane localisation. Studies of related genes in other species connect the family to reduced virulence and associations with grey mold, though these findings are not yet established for stcW itself.