laeA — Aspergillus nidulans FGSC A4

Summary

The Aspergillus nidulans gene laeA (ANIA_06749) on chromosome 1 encodes a SAM-dependent methyltransferase superfamily protein with methyltransferase activity. It is localized to the nucleus. This gene is associated with diorcinol anabolism, PR-toxin anabolism, penicillin G anabolism, gliotoxin anabolism, terrequinone A anabolism, carotenoid anabolism, carotene anabolism, inhibition of sterigmatocystin anabolism, methionine metabolism, pigmentation, fruiting body formation, perithecium development, sexual sporulation, negative regulation of sexual sporulation resulting in formation of a cellular spore, asexual reproduction, asexual sporulation, stem cell differentiation, and SIPS. Additionally, laeA is associated with germination rate and oxidative stress response. Related genes in other species also encode methyltransferase domain-containing proteins.