PP2A — Arabidopsis thaliana

Summary

AT1G69960 (PP2A) in Arabidopsis thaliana encodes a protein with protein serine/threonine phosphatase activity (EC 3.1.3.16), belonging to the PPA2-like and calcineurin-like phosphoprotein phosphatase families. The gene is associated with phosphorus deficiency tolerance, response to methionine, regulation of phosphatase activity, TOR signaling, and brassinosteroid signaling pathways. It has been linked to numerous agronomic traits including seed yield, biomass yield, root branching, lateral root length, leaf elongation rate, shoot fresh weight, seed longevity, and responses to cadmium, aluminum, nitrate, and phosphorus. The protein localizes to the PP2A complex, cytosol, nucleus, ER membrane, mitochondria, and plasmalemma. Studies of related genes in other species link the PP2A family to disease resistance, oxidative stress response, and S-type anion channel activation.