MYCGR3G98311 — Zymoseptoria tritici

Summary

MYCGR3G98311 (BCY1) on Zymoseptoria tritici chromosome 1 encodes the regulatory subunit MgBcy1 of the cAMP-dependent protein kinase (PKA) complex, possessing cAMP binding, PKA catalytic subunit binding, and cAMP-dependent protein kinase inhibitor activities. The gene is associated with cAMP signaling, positive regulation of asexual sporulation, asexual reproduction, autolysis, cellular responses to glucose and nitrogen starvation, osmotic response, glycogen anabolism, regulation of cell division, downregulation of nuclear division and Ras signal transduction, premeiotic DNA replication, karyogamy, and protein localization to the bud neck. The encoded protein localizes to the PKA complex, plasma membrane, cytosol, nucleus, and chromatin. Studies of related genes in other species link the BCY1 family to loss of pathogenicity, calcium sensitivity, and oxidative stress.