MYCGR3G100278 — Zymoseptoria tritici

Summary

MYCGR3G100278 (CREA, also known as MIG1) on Zymoseptoria tritici chromosome 5 encodes a C2H2-type zinc-finger transcription factor with DNA-binding and zinc-binding activity. The gene is associated with carbon catabolite repression, regulation of carbon utilization, and downregulation of transcription by glucose. It has been linked to DHN-melanin biosynthesis, teliospore formation, sexual flocculation, cell-substrate adhesion, micropexophagy, and responses to basic pH. Associations also include methanol breakdown, sucrose and maltose metabolism, ethanol and histidine anabolism, carotenoid anabolism, and regulation of phosphorylation and metabolism. The protein localizes to both the cytoplasm and nucleus. Studies of related genes in other species link the family to reduced virulence, as well as associations with carotenoid and carbohydrate content, biomass yield, calcium sensitivity, protein content, and oxidative stress.