POL — Triticum turgidum subsp. durum

Summary

TRITD7BV1G041140 (symbol POL, preferred name TtPOL) on durum wheat chromosome 7B encodes a DNA polymerase with DNA-directed DNA polymerase, DNA ligase (ATP), lyase, and 5′-deoxyribose phosphate activities, and binds DNA, ATP, manganese, and other metals. It contains DNA polymerase X, beta-like, lambda fingers, and BRCT domains. The gene is associated with base-excision repair, non-homologous end joining, nucleotide excision repair, double-strand break repair, DNA replication, and the DNA damage response, as well as responses to X-ray, UV-B, heat, arsenic, and bacterial defence. It is linked to traits including radiation and temperature stress responses, flowering time, disease tolerance, root morphology, and embryo development. Related genes in other species are linked to DNA double-strand break repair, ionizing radiation resistance, and telomere fusion, as well as heat stress memory, pathogen resistance, and stomatal development.