MDH — Triticum turgidum subsp. durum

Summary

TRITD7BV1G161710 (TtMDH) encodes a malate dehydrogenase with NAD-L-malate dehydrogenase activity (EC 1.1.1.37), belonging to the malate dehydrogenase type 1 family and containing lactate/malate dehydrogenase domains. In durum wheat, this gene is associated with malate metabolism, the TCA cycle, glyoxylate cycle, carboxylic acid metabolism, pH reduction, and chloroplast stroma protein import. It has been linked to responses to heat, cold, light stimulus, and bacterial defence, as well as embryo development, root development, and syngamy. The encoded protein localises to plastid stroma, chloroplast inner membrane, envelope, nucleoid, stromule, and mitochondrial lumen. Associations include respiration rate, photosynthetic rate, chloroplast development, high temperature stress, and oxidative stress response. Related genes in other species link the family to thermotolerance, thermomemory, plastid genome stability, and chaperone activity.