CAM1 — Sorghum bicolor

Summary

SORBI_3K043400 (SbCAM1) on sorghum chromosome super_88 encodes a J domain-containing protein with DnaJ and TPR domains. The gene product is associated with multiple molecular functions including Hsp70 protein binding, ATPase activator activity, S-nitrosoglutathione reductase activity, and vitamin Bt transporter activity. It is linked to protein folding in the endoplasmic reticulum, the ERAD pathway, cellular responses to heat, cold, drought and salinity, leaf senescence, seed development, and lignin biosynthesis. Associations with agronomic traits include photosynthetic rate, stomatal opening and closure, flowering time, disease tolerance, salt stress response, iron sensitivity and concentration, root development, and shoot branching. The protein localizes to the ER lumen, tonoplast, chloroplast envelope, vacuole, plastid, and chromatin. Studies of related genes in other species link the family to drought, salt, cold, freezing, and cadmium tolerance, seed germination, grain yield, and root development.