LDH — Sorghum bicolor

Summary

SbLDH (SORBI_3004G004400) on sorghum chromosome 4 encodes an L-lactate dehydrogenase with NAD+ activity (EC 1.1.1.27) and is also annotated with NAD-L-malate dehydrogenase activity, placing it in the lactate/malate dehydrogenase family. The gene is associated with lactate anabolism, pyruvate breakdown, fermentation, the TCA cycle, glyoxylate cycle, malate metabolism, carboxylic acid metabolism, cell wall modification, detoxification, and response to abscisic acid. It localises to the cytosol, cytoplasm, and plasmalemma. Traits linked to SbLDH include stem thickness, respiration rate (CO2), and plant height. Studies of related genes in other species connect the family to cold tolerance, drought tolerance, seed germination, chlorophyll content, photochemical quenching, and sugar content.