CYP — Sorghum bicolor

Summary

SORBI_3004G018400 (SbSQN, also known as CYP) on sorghum chromosome 4 encodes a cyclophilin-type peptidyl-prolyl cis-trans isomerase (EC 5.2.1.8) with additional annotated molecular functions including GTP:GDP antiporter activity, U5 and U2 snRNA binding, cyclosporin A binding, histone binding, chromatin binding, calcium ion binding, ATP hydrolase activity, and structural constituent of the ribosome. The gene is associated with regulation of ARF protein signal transduction, protein phosphorylation, protein refolding, alternative mRNA splicing, basipetal auxin transport, secondary metabolite biosynthesis, and responses to chlorate, mannitol, and arsenic. It has been linked to numerous agronomic traits including variegated leaf, bacterial disease response, temperature stress response, starch grain synthesis, sucrose content, phototropism, root hair length, root mass density, chloroplast development, jasmonic acid content, arsenic concentration, stomatal opening, leaf senescence, seed growth and development, flowering time, and oxidative stress response. Studies of related genes in other species connect the family to auxin transport, root development, stress tolerance, and grain weight.