AM25 — Sorghum bicolor

Summary

SORBI_3004G102200 (SbAM25) on sorghum chromosome 4 encodes an aquaporin NIP1-1 protein, a member of the major intrinsic protein (MIP) family. The gene product exhibits transmembrane transporter activities for lactate, arsenite, silicate, glycerol, borate, urea, and water, and is associated with the transport of these substrates, including hydrogen peroxide. SbAM25 is associated with responses to boron, arsenic, hypoxia, and glucose, as well as with phenylpropanoid biosynthesis, defense response regulation, and nodulation. The protein localizes to the plasma membrane, lateral plasma membrane, peribacteroid membrane, Casparian strip, and endoplasmic reticulum. Phenotypic associations connect SbAM25 to boron uptake and deficiency tolerance, arsenite and arsenate tolerance, aluminum tolerance and translocation, urea uptake, pollen development, and xylem and root localization.