CYP — Sorghum bicolor

Summary

SORBI_3004G162000, also known as SbSQN or CYP, encodes a cyclophilin-type peptidyl-prolyl cis-trans isomerase (PPIase) with EC 5.2.1.8 activity, enabling cyclosporin A binding and cis-trans proline isomerase activity. This sorghum gene on chromosome 4 is associated with protein folding, regulation of protein refolding, activation of secondary metabolite biosynthesis, secondary metabolite biosynthesis, and secondary metabolism. It is linked to responses to abscisic acid, salt, and mannitol, as well as activation of the salinity response. The product localizes to the chloroplast stroma, cytosol, plasmalemma, cytoplasm, and nucleus. Associations with lateral root initiation and development, root structure development, and vegetative structure development connect it to growth and developmental processes. Studies of related genes in other species link the family to peptidyl-prolyl cis/trans isomerization of OsIAA11 and interactions with auxin-related proteins.