LDH — Sorghum bicolor

Summary

SbLDH (SORBI_3004G004500) on sorghum chromosome 4 encodes a protein with L-lactate dehydrogenase (NAD+) and NAD-L-malate dehydrogenase activities (EC 1.1.1.27), belonging to the lactate/malate dehydrogenase superfamily. The gene is associated with lactate anabolism, pyruvate breakdown, lactate and malate metabolism, the glyoxylate cycle, fermentation, the TCA cycle, cell wall modification, detoxification, and response to abscisic acid. Its product localises to the mitochondrial lumen, cytosol, plasmalemma, and cytoplasm. SbLDH is linked to stem thickness, respiration rate (CO2-based), and plant height. Studies of related genes in other species connect the family to total soluble sugar and sugar content, cold and drought tolerance, chlorophyll content, photochemical quenching, seed germination, and salt tolerance.