ACL — Sorghum bicolor

Summary

SORBI_3003G417350 (SbACL) encodes a member of the MES/HNL family of alpha/beta hydrolase-fold proteins with carboxylesterase, lipase, and specific esterase activities toward polyneuridine aldehyde, methyl salicylate, methyl jasmonate, and methyl indole-3-acetate. In sorghum, this gene is associated with the metabolism of nicotinate, salicylic acid, jasmonic acid, and dhurrin, as well as with indole alkaloid and oxylipin biosynthesis. It is linked to systemic acquired resistance, innate immunity, defence against fungi, and responses to water, cold, UV-B, and hypoxia. The encoded protein localises to the vacuole, cytosol, and nucleus. Associations with seed germination and NAD biosynthesis have also been noted. Studies of related genes in other species connect the family to triterpene and sterol accumulation and methylesterase activity, while sequence similarity links SbACL to root dry weight, pollen fertility, anthocyanin content, and seed growth traits.