P5CS — Sorghum bicolor

Summary

SORBI_3003G356000 (SbP5CS) encodes a protein with glutamate 5-kinase activity (EC 2.7.2.11) and glutamylphosphate reductase activity (EC 1.2.1.41), and possesses D1-pyrroline-5-carboxylate synthetase activity. This sorghum gene on chromosome 3 is associated with proline biosynthesis and metabolism, cellular water homeostasis, and responses to desiccation, osmotic stress, salinity, oxidative stress, and abscisic acid. It is also linked to the ascorbate-glutathione cycle, detoxification, root development, embryo development, and the transition to reproductive phase. The encoded protein localizes to the cytoplasm, mitochondria, Golgi complex, and plasmodesmata. SbP5CS is associated with grain yield, grain filling period, water use efficiency, photosynthetic rate, stay green trait, root length and dry weight, cell membrane stability, and proline content. Studies of related genes in other species link the family to drought, salt, and osmotic stress tolerance, root elongation, and flowering time.