AS2 — Phaseolus vulgaris

Summary

PHAVU_011G197300 (PvAS2) encodes a LOB domain-containing protein with sequence-specific dsDNA binding, histone H3K27 trimethylase activity, transcription corepressor binding, DNA-binding transcription activator activity, ssRNA binding, transcription cis-regulatory region binding, identical protein binding, protein homodimerization activity, DNA binding, DNA binding transcription factor activity, and protein binding. In French bean, this gene is associated with adaxial/abaxial axis specification, proximal/distal pattern formation, leaf formation, cotyledon morphogenesis, xylem development, and regulation of endosperm development and innate immune response. It localizes to the nucleus, nucleolus, condensed chromosome, chromatin silencing complex, and Cul4-RING E3 ubiquitin ligase complex. PvAS2 is linked to numerous traits including leaf flexibility, leaf area, leaf margin morphology, petal color, flower abscission zone, selenium and sulfur content, brassinosteroid content, nitrate transport, oleic acid content, plant male sterility, and vegetative to reproductive phase transition. Studies of related genes in other species connect the AS2 family to leaf shape, leaf cell fate specification, gynoecium and fruit patterning, H3K27me3 histone modification, seed oil accumulation, and viral disease resistance.