C3H4 — Phaseolus vulgaris

Summary

PvC3H4 (PHAVU_L002537) on French bean chromosome MU967755.1 encodes a CCCH zinc-finger and RRM-domain-containing protein that binds pre-mRNA, U6 snRNA, poly-A, mRNA, DNA, and transcription cis-regulatory regions, and has DNA-binding transcription factor activity. The gene is associated with alternative mRNA splicing via the spliceosome, mRNA processing, polyamine metabolism, detoxification, cellular response to heat, transition from vegetative to reproductive phase, embryo development ending in seed dormancy, defence responses to bacteria and fungi, and regulation of transcription. It is linked to starch grain synthesis, meristem and shoot apical meristem development, transpiration rate, cell cycle, embryo development, and flowering time traits. The protein localises to the spliceosome, Prp19 complex, stress granules, nucleolus, cytosol, nucleus, mitochondria, and extracellular space. Studies of related genes in other species link the family to flowering time, cell death, and starch biosynthesis.