ADH — Phaseolus vulgaris

Summary

PHAVU_001G067300 (PvADH) on chromosome 1 of French bean encodes an alcohol dehydrogenase with S-(hydroxymethyl)glutathione dehydrogenase [NAD(P)+] and aldo-keto reductase (NAD) activities, and is associated with protein homodimerization activity and zinc binding. The gene is associated with responses to hypoxia, flooding, water, cold, hydrogen peroxide, sucrose, estradiol, caffeine, and salinity, as well as cellular respiration, methanal catabolism, and osmotic responses. It is linked to traits including drought tolerance, seed weight, seed size, germination rate, photosynthetic rate, pollen fertility, herbicide sensitivity, disease tolerance, and salt tolerance. Phenotypic associations include waterlogging tolerance, submergence tolerance, cold tolerance, fermentation, aldehyde detoxification, and clubroot susceptibility. Studies of related genes in other species link the family to low oxygen tolerance, cold and dehydration stress responses, pathogen resistance, and drought resistance.