RB — Phaseolus vulgaris

Summary

PHAVU_011G201200 (PvRB) on chromosome 11 of French bean encodes a retinoblastoma-related (RB) protein containing RB_A, RB_B, and RB_N domains and a cyclin-like superfamily domain. The product has DNA-binding transcription activator activity, RNA polymerase II-specific, transcription corepressor binding, CDK activity, and protein serine/threonine kinase activity. PvRB is associated with negative regulation of the G1/S transition of the mitotic cell cycle, regulation of cytokinesis, stem cell population maintenance, palisade mesophyll development, stomatal complex formation, and epigenetic programming in the endosperm. It localizes to the microsporocyte nucleus, generative cell nucleus, chromatin silencing complex, and spindle. The gene is linked to traits including photoperiod sensitivity, flowering time, seed growth and development, root morphology, and oleic acid content. Related genes in other species are linked to cell cycle control, stem cell maintenance, drought stress response, and stomatal index.