TN2 — Phaseolus vulgaris

Summary

PvTN2 (PHAVU_002G098200) on chromosome 2 of French bean encodes a protein with domains including NB-ARC, TIR, and leucine-rich repeats, and exhibits ATP hydrolase, NADP nucleosidase, lipase, and DNA-binding transcription factor activities. The gene is associated with defense responses to Gram-negative bacteria, viruses, and insects, as well as systemic acquired resistance via salicylic acid signaling, callose deposition, and regulation of hydrogen peroxide metabolism. It is linked to responses to UV, ozone, hypoxia, and singlet oxygen, and to processes including leaf abscission, stomatal closure, and root meristem size regulation. Associations with agronomic traits include biomass yield, seed yield, water use efficiency, disease tolerance, anthocyanin content, and responses to low temperature, oxidative stress, and aluminum. Studies of related genes in other species connect the family to resistance against Pseudomonas syringae, Colletotrichum higginsianum, and Leptosphaeria maculans, as well as to chilling tolerance and autoimmunity.