CAD — Nicotiana attenuata

Summary

A4A49_64415 (CAD) in coyote tobacco (Nicotiana attenuata) encodes a cinnamyl-alcohol dehydrogenase-like protein with geraniol dehydrogenase, vomilenine reductase, mannitol dehydrogenase, 8-hydroxygeraniol dehydrogenase, and cinnamyl-alcohol dehydrogenase activities, along with oxidoreductase activity acting on CH-OH groups with NAD or NADP as acceptor, and metal and zinc binding. The gene is associated with oviposition, glycan biosynthesis, primary metabolism, pigmentation, phenylpropanoid metabolism, photorespiration, detoxification, lignin anabolism, flavonoid anabolism, alkaloid metabolism, and carbohydrate metabolism, and its product localizes to the cytoplasm. It has been linked to starch mobilization and lignin content. Studies of related genes in other species connect the family to alcohol dehydrogenases such as CAD3, ADH9, ELI3, MTD, GEDH1, VR, RR6, and 10HGO, and to EC numbers 1.1.1.183, 1.5.1.32, 1.1.1.324, 1.1.1.255, 1.1.1.195, and 1.3.1.-.