ARF — Nicotiana attenuata

Summary

A4A49_64979 (ARF) in coyote tobacco (Nicotiana attenuata) encodes a small GTPase of the ARF/SAR family, with annotated molecular functions including G protein activity, phosphatidylinositol kinase activity, and phospholipase activator activity. This gene is associated with vesicle-mediated transport to the plasma membrane, Golgi organization, ER-to-Golgi transport, and protein retention in the ER lumen. It is associated with nicotine and alkaloid anabolism, regulation of auxin metabolism, and blue light signaling. Associations with agronomically relevant traits include biomass yield, water use efficiency, days to flowering, disease tolerance, oxidative stress response, low temperature stress response, abscisic acid sensitivity, and ethylene sensitivity. The gene is also linked to phototropism, leaf senescence, root and shoot development, and stomatal resistance. Studies of related genes in other species connect the ARF family to vesicular transport, phototropic responses, and stress tolerance.