FLS2 — Nicotiana attenuata

Summary

A4A49_65715, the FLS2 gene in coyote tobacco (Nicotiana attenuata) on scaffold30718, encodes a leucine-rich repeat receptor-like kinase (LRR-RLK) with transmembrane receptor serine/threonine kinase activity, ATP binding, and signaling receptor activity. It is associated with pattern-triggered immunity (PTI) signaling, activation of innate immune response, defense response to parasitic plants, and upregulation of defense responses to bacteria. The gene is linked to viral translation, membrane fission, endocytosis, microtubule bundling, and developmental processes including megasporogenesis, microsporogenesis, anther wall tapetum development, stomatal complex morphogenesis, and skotomorphogenesis. The product localizes to the plasma membrane, ER membrane, endosome, and nucleus. Studies of related genes in other species connect the LRR-RLK family to immune perception and developmental signaling.